Ephedrine production from suspension cultures of Ephedra alata L. callus

Biotransformation for L-ephedrine production.

L-ephedrine is widely used in pharmaceutical preparations as a decongestant and anti-asthmatic compound. One of the key intermediates in its production is L-phenylacetylcarbinol (L-PAC) which can be obtained either from plants (Ephedra sp.), chemical synthesis involving resolution of a racemic mixture, or by biotransformation of benzaldehyde using various yeasts. In the present review, recent s...

The Ephedrine Assay of Chinese Ephedra.*

As set forth in a recent note we have shown that Chinese Ma Huang is obtained from various species of Ephedra, E. eguisetina, Bunge; E. sinica, Stapf ; and E. mahuang, Liu. So far there has been no differentiation made between the various samples of this drug which occur upon the Chinese market. However, irrespective of the possible variation in the drug samples we consider i t is essential tha...

[Acridine-alkaloids from callus cultures of Ruta graveolens L].

Rutacridone, 1-hydroxy-A-methylacridone, and l-hydroxy-3-methoxy-A-methylacridone have been isolated for the first time from callus cultures, which had been obtained from meristematic stem cells of Ruta graveolens L. The alkaloids were identified by co-chromatography with authentic compounds, by IR spectra, and by electronic spectra before and after addition of A1C13 . The use of the bathochrom...

Optimization of callus and cell suspension cultures of Barringtonia racemosa (Lecythidaceae family) for lycopene production

Lycopene is present in a range of fresh fruits and vegetables, especially in the leaves of Barringtonia racemosa. The traditional lycopene extraction from the plant is being employed instead of an easy propagation technique like cell culture process from the leaf explants. We intend to assess how lycopene could be extracted via tissue culture under light (illuminance: 8,200 lux under white fluo...

Ephedra/ephedrine: cardiovascular and CNS effects.